RPL23AP11

Across TCGA pan-cancer cohorts, RPL23AP11 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RPL23AP11 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher RPL23AP11 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RPL23AP11 expression acts as an unfavorable survival marker, although some lineages such as CESC and LUSC show a favorable association.

CESC, STAD, and LUSC are the cancer types where RPL23AP11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	II,III,IV	0.687	0.278	<.001	122	view →
STAD	DFS	Quartile	II,III,IV	0.395	0.630	<.001	80	view →
LUSC	OS	Median	All	0.742	0.584	<.001	64	view →
BLCA	OS	Quartile	IV	0.410	0.670	.002	53	view →
UCS	DFS	Median	IV	0.885	0.440	.015	22	view →
LAML	DFS	Tertile	All	0.635	0.224	<.001	20	view →
PAAD	OS	Median	II,III,IV	0.665	0.361	.019	15	view →
UVM	OS	Tertile	III,IV	0.601	0.892	.043	9	view →
KIRP	OS	Quartile	III,IV	0.331	0.599	.017	9	view →
KIRC	DFS	Median	IV	0.500	0.261	.021	8	view →
COAD	DFS	Median	IV	0.350	0.598	.014	7	view →
BRCA	DFS	Median	IV	0.522	0.856	.024	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RPL23AP11–CESC (OS)

Open the CESC breakdown →