Across TCGA patient cohorts, RPL23A protein abundance is significantly associated with the RNA expression of many other genes, with 13,644 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RPL23A-associated genes across cancer lineages are SPIN1, CREB1, and TTBK2. Each is linked with RPL23A in more than 5 cancer types. Because this analysis shows association rather than direction, both RPL23A-to-partner and partner-to-RPL23A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL23A→partner) and Y-score (partner→RPL23A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SPIN1 →	-0.559	-0.291	.002	<.001	2	6
HNSC	CREB1 →	-0.351	-0.219	.001	<.001	3	5
LSCC	TTBK2 →	-0.560	-0.280	<.001	<.001	3	5
COAD	SECISBP2L →	-0.407	-0.225	<.001	.006	3	5
COAD	ZBTB4 →	-0.529	-0.308	<.001	<.001	3	5
BRCA	KLHDC1 →	-0.566	-0.219	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,644 associations by consensus.

Exploration

RPL23A survival (RNA) · tumor vs normal (RNA) · all RPL23A data types