RPL23A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPL23A mutation is significantly associated with the RNA expression of many other genes, with 570 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL23A-associated genes across cancer lineages are RNU6-225P, MIR132, and RN7SKP136. Each is linked with RPL23A in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL23A-to-partner and partner-to-RPL23A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL23A→partner) and Y-score (partner→RPL23A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNU6-225P →+0.237+6.055<.001<.00132
UCECMIR132 →+0.441+3.601<.001<.00132
BLCARN7SKP136 →+0.048+4.229<.001.00632
BLCAMTND2P4 →+0.088+3.792<.001<.00132
BLCAIMP3P1 →+0.032+4.455<.001.00532
LUADRNU6-864P →+0.253+7.930<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 570 associations by consensus.

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