RPL22P7

Across TCGA pan-cancer cohorts, RPL22P7 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RPL22P7 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RPL22P7 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL22P7 expression acts as an unfavorable survival marker, although some lineages such as LAML and ESCA show a favorable association.

UCEC, CHOL, and ACC are the cancer types where RPL22P7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	III,IV	0.675	0.867	.001	124	view →
CHOL	OS	Tertile	II,III,IV	0.019	0.675	<.001	54	view →
ACC	OS	Tertile	II,III,IV	0.693	0.913	.010	36	view →
STAD	OS	Tertile	II,III,IV	0.564	0.806	.011	27	view →
PAAD	OS	Tertile	All	0.307	0.507	.015	24	view →
LAML	DFS	Quartile	All	0.656	0.335	.020	16	view →
DLBC	OS	Tertile	III,IV	0.310	1.000	.021	13	view →
SARC	OS	Tertile	All	0.734	0.860	.017	9	view →
ESCA	OS	Quartile	II,III,IV	0.550	0.288	.039	7	view →
THYM	DFS	Tertile	III,IV	0.214	1.000	.017	6	view →
THCA	OS	Median	III,IV	1.000	0.958	.045	6	view →
LGG	OS	Tertile	All	0.604	0.484	.027	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RPL22P7–UCEC (OS)

Open the UCEC breakdown →