Across TCGA pan-cancer cohorts, RPL22P14 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL22P14’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL22P14 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL22P14 is over-expressed in tumor, although a few such as KIRC and LUAD show the opposite, repressed pattern.

KIRC, LUAD, and KIRC are the cancer types where RPL22P14 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL22P14 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	−0.031	.036	2	view →
LUAD	Female	All	−0.056	.019	1	view →
KIRC	Male	All	+0.031	.009	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 2 lineages.

Exploration

Same gene, other analysis: RPL22P14 RNA expression & survival · all RPL22P14 data types