Across TCGA pan-cancer cohorts, RPL22P10 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPL22P10’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RPL22P10 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL22P10 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KICH, COAD, and THCA are the cancer types where RPL22P10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL22P10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.078	.002	4	view →
COAD	Male	III,IV	+0.185	.025	1	view →
THCA	Female	II,III,IV	+0.100	.006	1	view →
LUAD	Male	All	+0.079	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RPL22P10 RNA expression & survival · all RPL22P10 data types