RPL22L1

Across TCGA patient cohorts, RPL22L1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,002 significant associations in total. COAD shows the largest number of these associations.

The most reproducible RPL22L1-associated genes across cancer lineages are LRRC47, GPR153, and CEP104. Each is linked with RPL22L1 in more than 5 cancer types. Because this analysis shows association rather than direction, both RPL22L1-to-partner and partner-to-RPL22L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPL22L1 versus LRRC47 in OV, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL22L1→partner) and Y-score (partner→RPL22L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LRRC47 →	-0.504	-0.680	.004	.008	3	6
COAD	GPR153 →	-1.179	-1.462	<.001	<.001	3	5
OV	CEP104 →	-0.585	-0.845	.005	.002	3	5
OV	DNAJC11 →	-0.526	-0.678	.003	.002	3	5
BRCA	DNAJC16 →	-0.528	-0.762	<.001	<.001	3	5
CCRCC	RPL22 →	-0.453	-0.579	.008	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,002 associations by consensus.

RPL22L1 vs LRRC47 — OV

Explore this scatter interactively →