RPL22L1

Across TCGA patient cohorts, RPL22L1 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL22L1-associated genes across cancer lineages are RNU6-1265P, RN7SKP88, and MIR3675. Each is linked with RPL22L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL22L1-to-partner and partner-to-RPL22L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1265P grouped by RPL22L1-low versus RPL22L1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL22L1→partner) and Y-score (partner→RPL22L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-1265P →	+0.861	+6.382	<.001	.001	3	2
BRCA	RN7SKP88 →	+0.089	+8.057	<.001	.005	3	1
BRCA	MIR3675 →	+0.278	+7.471	<.001	.008	3	1
UCEC	URGCP-MRPS24 →	+0.402	+3.969	<.001	.001	3	1
BRCA	RNU1-23P →	+0.329	+6.382	<.001	.001	3	1
BRCA	RNU6-394P →	+0.188	+7.471	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

RNU6-1265P by RPL22L1 expression — BRCA

Explore this box plot interactively →