RPL22

Across TCGA patient cohorts, RPL22 protein abundance is significantly associated with the RNA expression of many other genes, with 14,216 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPL22-associated genes across cancer lineages are CTSG, PTPRB, and TAL1. Each is linked with RPL22 in more than 7 cancer types. Because this analysis shows association rather than direction, both RPL22-to-partner and partner-to-RPL22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPL22 versus CTSG in BRCA, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL22→partner) and Y-score (partner→RPL22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CTSG →	-1.247	-0.472	<.001	<.001	3	8
BRCA	PTPRB →	-0.839	-0.391	<.001	<.001	3	6
CCRCC	TAL1 →	-0.710	-0.246	.001	<.001	3	6
BRCA	S1PR1 →	-0.998	-0.469	<.001	<.001	3	6
BRCA	TPSAB1 →	-1.370	-0.369	<.001	<.001	3	6
HNSC	SELP →	-1.286	-0.805	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,216 associations by consensus.

RPL22 vs CTSG — BRCA

Explore this scatter interactively →