RPL22

Across TCGA patient cohorts, RPL22 protein abundance is significantly associated with the protein abundance of many other proteins, with 28,710 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPL22-associated proteins across cancer lineages are RPL9, RPS7, and RPL23. Each is linked with RPL22 in more than 9 cancer types. Because this analysis shows association rather than direction, both RPL22-to-partner and partner-to-RPL22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPL22 versus RPL9 in UCEC, with a Pearson correlation of 0.62.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL22→partner) and Y-score (partner→RPL22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL9 →	+0.417	+0.529	<.001	<.001	3	10
COAD	RPS7 →	+0.370	+0.247	<.001	<.001	3	10
OV	RPL23 →	+0.572	+0.867	<.001	<.001	3	9
PDAC	RPS15 →	+0.433	+0.557	<.001	<.001	3	9
HNSC	RPS24 →	+0.428	+0.590	<.001	<.001	3	9
PDAC	RPS4X →	+0.353	+0.404	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 28,710 associations by consensus.

RPL22 vs RPL9 — UCEC

Explore this scatter interactively →