Across TCGA pan-cancer cohorts, RPL21P92 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPL21P92’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RPL21P92 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL21P92 is over-expressed in tumor, although a few such as THCA and PAAD show the opposite, repressed pattern.

THCA, PAAD, and BRCA are the cancer types where RPL21P92 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL21P92 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.049	.006	5	view →
PAAD	Male	All	−0.200	.009	2	view →
BRCA	All	II,III,IV	+0.052	.047	2	view →
KIRC	Male	All	+0.040	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RPL21P92 RNA expression & survival · all RPL21P92 data types