RPL21P90

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL21P90 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated RPL21P90 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RPL21P90 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL21P90 expression acts as an unfavorable survival marker, although some lineages such as THYM and LGG show a favorable association.

LUSC, ACC, and KIRC are the cancer types where RPL21P90 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUSCDFSQuartileIII,IV0.1600.904<.00165view →
ACCDFSQuartileII,III,IV0.2820.613<.00148view →
KIRCDFSQuartileAll0.7290.885.01126view →
KICHDFSQuartileII,III,IV0.3640.898.00112view →
HNSCDFSMedianII,III,IV0.2680.441.00310view →
READDFSTertileAll0.6890.929.0048view →
THYMDFSTertileAll0.9490.508.0107view →
UVMOSTertileAll0.7170.945.0236view →
LGGOSTertileAll0.9310.855.0196view →
LAMLDFSMedianAll0.5570.349.0266view →
BLCADFSTertileIII,IV0.6200.393.0375view →
DLBCDFSMedianIV0.1950.923.0385view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

Exploration