Across TCGA pan-cancer cohorts, RPL21P50 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RPL21P50’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where RPL21P50 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL21P50 is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.

ESCA are the cancer types where RPL21P50 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL21P50 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	Male	All	−0.178	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: RPL21P50 RNA expression & survival · all RPL21P50 data types