RPL21P44

Across TCGA pan-cancer cohorts, RPL21P44 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RPL21P44’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL21P44 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL21P44 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

KIRC, BRCA, and THCA are the cancer types where RPL21P44 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL21P44 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.149	.001	9	view →
BRCA	All	III,IV	−0.479	<.001	6	view →
THCA	All	All	−0.156	<.001	6	view →
KICH	All	IV	+0.367	.012	5	view →
LUSC	All	All	−0.345	<.001	5	view →
UCEC	All	IV	−0.360	.003	4	view →
CHOL	All	All	+0.462	.001	2	view →
LUAD	All	III,IV	−0.423	.007	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RPL21P44–KIRC

Open the KIRC breakdown →