RPL21P4

Across TCGA pan-cancer cohorts, RPL21P4 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RPL21P4 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RPL21P4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RPL21P4 expression acts as an unfavorable survival marker, although some lineages such as MESO and HNSC show a favorable association.

MESO, HNSC, and THCA are the cancer types where RPL21P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.504	0.266	<.001	102	view →
HNSC	DFS	Median	III,IV	0.440	0.207	<.001	56	view →
THCA	OS	Median	III,IV	0.989	0.891	.002	53	view →
OV	OS	Quartile	II,III,IV	0.637	0.723	.020	36	view →
KIRC	DFS	Quartile	IV	0.232	0.602	<.001	32	view →
COAD	DFS	Median	II,III,IV	0.546	0.734	.001	31	view →
ACC	OS	Quartile	All	0.451	1.000	.009	25	view →
UCS	OS	Quartile	II,III,IV	0.439	0.928	.001	24	view →
LUAD	DFS	Tertile	IV	0.787	0.263	.011	19	view →
KIRP	OS	Tertile	All	0.497	0.868	.002	18	view →
CHOL	OS	Tertile	All	0.314	0.876	.013	12	view →
BLCA	OS	Quartile	II,III,IV	0.714	0.569	.024	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RPL21P4–MESO (OS)

Open the MESO breakdown →