RPL21P30

Across TCGA pan-cancer cohorts, RPL21P30 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPL21P30’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RPL21P30 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL21P30 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KICH, PAAD, and UCEC are the cancer types where RPL21P30 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL21P30 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.083	.015	5	view →
PAAD	Male	All	+0.290	.018	2	view →
UCEC	All	All	−0.229	.003	2	view →
THCA	Female	All	−0.109	.030	2	view →
KIRC	All	IV	+0.069	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RPL21P30–KICH

Open the KICH breakdown →