RPL21P13

Across TCGA patient cohorts, RPL21P13 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL21P13-associated genes across cancer lineages are RNA5-8SN1, RNU6-328P, and HIKESHIP1. Each is linked with RPL21P13 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL21P13-to-partner and partner-to-RPL21P13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5-8SN1 grouped by RPL21P13-low versus RPL21P13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL21P13→partner) and Y-score (partner→RPL21P13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5-8SN1 →	+0.778	+5.694	<.001	.003	3	1
SKCM	RNU6-328P →	+0.230	+4.199	<.001	.009	3	1
SKCM	HIKESHIP1 →	+0.366	+3.911	.001	.004	3	1
SKCM	HSPE1P28 →	+0.130	+4.328	<.001	.007	3	1
UCEC	FAM25G →	+0.256	+5.852	<.001	.003	3	1
UCEC	RNA5SP109 →	+0.793	+6.722	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

RNA5-8SN1 by RPL21P13 expression — UCEC

Explore this box plot interactively →