RPL21P111

Across TCGA pan-cancer cohorts, RPL21P111 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPL21P111’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RPL21P111 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL21P111 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

BRCA, THCA, and LIHC are the cancer types where RPL21P111 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL21P111 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.060	.002	4	view →
THCA	Female	All	−0.120	.004	3	view →
LIHC	Male	All	+0.037	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RPL21P111–BRCA

Open the BRCA breakdown →