RPL21P109

Across TCGA pan-cancer cohorts, RPL21P109 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL21P109’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL21P109 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL21P109 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

KIRC and BRCA are the cancer types where RPL21P109 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL21P109 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.023	.030	4	view →
BRCA	Female	All	+0.118	.034	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RPL21P109–KIRC

Open the KIRC breakdown →