RPL21P106

Across TCGA patient cohorts, RPL21P106 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,562 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RPL21P106-associated GO terms across cancer lineages are Telomerase holoenzyme complex assembly, Mitochondrial gene expression, and Positive regulation of signal transduction by p53 class mediator. Each is linked with RPL21P106 in more than 15 cancer types. Because this analysis shows association rather than direction, both RPL21P106-to-partner and partner-to-RPL21P106 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomerase holoenzyme complex assembly grouped by RPL21P106-low versus RPL21P106-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL21P106→partner) and Y-score (partner→RPL21P106) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Telomerase holoenzyme complex assembly →	+0.045	+0.220	<.001	<.001	3	16
STAD	Mitochondrial gene expression →	+0.077	+0.415	<.001	<.001	3	15
STAD	Positive regulation of signal transduction by p53 class mediator →	+0.060	+0.338	<.001	<.001	3	15
STAD	Cellular respiration →	+0.071	+0.363	<.001	<.001	3	15
STAD	NADH dehydrogenase complex assembly →	+0.073	+0.365	<.001	<.001	3	14
STAD	Ribosomal large subunit assembly →	+0.072	+0.330	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,562 associations by consensus.

Telomerase holoenzyme complex assembly by RPL21P106 expression — ESCA

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