RPL18AP15

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL18AP15 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPL18AP15’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPL18AP15 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL18AP15 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

COAD, LIHC, and KIRC are the cancer types where RPL18AP15 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL18AP15 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADAllAll+0.216.0029view →
LIHCFemaleII,III,IV+0.114.0024view →
KIRCAllAll+0.054.0043view →
LUSCFemaleIII,IV+0.185.0062view →
THCAAllAll−0.055.0102view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RPL18AP15–COAD

Tumor-vs-normal expression box plot for RPL18AP15 RNA in COAD.

Open the COAD breakdown →

Exploration