RPL18

Across TCGA patient cohorts, RPL18 protein abundance is significantly associated with the RNA expression of many other genes, with 13,014 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPL18-associated genes across cancer lineages are HNMT, N4BP2L1, and SAP30L. Each is linked with RPL18 in more than 4 cancer types. Because this analysis shows association rather than direction, both RPL18-to-partner and partner-to-RPL18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPL18 versus HNMT in HNSC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL18→partner) and Y-score (partner→RPL18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HNMT →	-0.832	-0.345	<.001	<.001	3	5
HNSC	N4BP2L1 →	-0.686	-0.263	<.001	<.001	3	5
HNSC	SAP30L →	-0.440	-0.225	.005	.003	3	5
BRCA	PDZK1 →	-1.524	-0.259	.004	.006	3	5
CCRCC	F8 →	-0.947	-0.241	.004	<.001	3	5
BRCA	PGR →	-2.489	-0.431	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,014 associations by consensus.

RPL18 vs HNMT — HNSC

Explore this scatter interactively →