Across TCGA pan-cancer cohorts, RPL17P44 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL17P44’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where RPL17P44 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL17P44 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.
COAD and LUAD are the cancer types where RPL17P44 tumor–normal differential expression is most reproducible.