RPL17

Across TCGA patient cohorts, RPL17 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL17-associated genes across cancer lineages are RPS15AP32, MIR3155A, and MIR4711. Each is linked with RPL17 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL17-to-partner and partner-to-RPL17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS15AP32 grouped by RPL17-low versus RPL17-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL17→partner) and Y-score (partner→RPL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS15AP32 →	+0.259	+5.420	.003	.005	3	2
UCEC	MIR3155A →	+0.827	+5.299	<.001	.006	3	1
UCEC	MIR4711 →	+0.950	+5.771	<.001	.003	3	1
UCEC	SNORD116-22 →	+0.797	+5.852	<.001	.003	3	1
BLCA	MIR638 →	+0.419	+7.640	<.001	.009	3	1
UCEC	SSXP1 →	+0.213	+5.694	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

RPS15AP32 by RPL17 expression — UCEC

Explore this box plot interactively →