RPL17

Across TCGA cell cohorts, RPL17 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,079 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RPL17-associated GO terms across cancer lineages are Negative regulation of apoptotic signaling pathway, Response to unfolded protein, and Membrane protein ectodomain proteolysis. Each is linked with RPL17 in more than 12 cancer types. Because this analysis shows association rather than direction, both RPL17-to-partner and partner-to-RPL17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of apoptotic signaling pathway grouped by RPL17-low versus RPL17-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL17→partner) and Y-score (partner→RPL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of apoptotic signaling pathway →	-0.063	-0.700	<.001	<.001	3	13
BREAST	Response to unfolded protein →	-0.083	-1.202	<.001	<.001	3	11
STOMACH	Membrane protein ectodomain proteolysis →	-0.154	-1.197	.002	<.001	3	11
SKIN	Regulation of apoptotic signaling pathway →	-0.048	-0.547	<.001	<.001	3	11
BREAST	Cellular response to unfolded protein →	-0.066	-1.057	<.001	<.001	3	11
PANCREAS	Response to topologically incorrect protein →	-0.053	-0.512	.002	.008	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,079 associations by consensus.

Negative regulation of apoptotic signaling pathway by RPL17 expression — BLOOD_Lymphoma

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