RPL17-C18orf32

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL17-C18orf32 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RPL17-C18orf32 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RPL17-C18orf32 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL17-C18orf32 expression acts as an unfavorable survival marker, although some lineages such as BRCA and GBM show a favorable association.

HNSC, BRCA, and ACC are the cancer types where RPL17-C18orf32 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCDFSQuartileII,III,IV0.4510.624<.00177view →
BRCADFSQuartileAll0.9350.878.00445view →
ACCOSTertileII,III,IV0.1930.853<.00140view →
GBMOSQuartileAll0.6950.318<.00130view →
SKCMDFSTertileIV0.1110.694.00419view →
KIRCDFSTertileII,III,IV0.6010.796.00116view →
CESCDFSMedianII,III,IV0.8610.700.00612view →
DLBCDFSMedianIII,IV0.3830.984.04312view →
MESODFSQuartileIII,IV0.5340.335.02610view →
CHOLDFSTertileIV0.9500.406.0409view →
LUADDFSTertileIII,IV0.7820.421.0219view →
THYMDFSMedianII,III,IV0.9460.527.0087view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

Exploration