RPL15

Across TCGA pan-cancer cohorts, RPL15 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RPL15 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher RPL15 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RPL15 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

LSCC, LUAD, and CCRCC are the cancer types where RPL15 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	All	0.830	0.573	.019	22	view →
LUAD	DFS	Quartile	All	0.802	0.415	.005	19	view →
CCRCC	DFS	Tertile	All	0.633	0.834	.033	7	view →
HNSC	OS	Tertile	II,III,IV	1.000	0.945	.043	4	view →
GBM	OS	Quartile	All	0.675	0.276	.028	3	view →
PDAC	OS	Median	IV	0.491	0.836	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RPL15–LSCC (DFS)

Open the LSCC breakdown →