RPL13A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPL13A mutation is significantly associated with the RNA expression of many other genes, with 2,559 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL13A-associated genes across cancer lineages are RN7SL122P, S100A11P9, and CICP6. Each is linked with RPL13A in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL13A-to-partner and partner-to-RPL13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL122P grouped by RPL13A-low versus RPL13A-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL13A→partner) and Y-score (partner→RPL13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL122P →+0.086+4.559<.001.00632
CESCS100A11P9 →+0.827+3.760<.001.00732
HNSCCICP6 →+0.031+5.124<.001.00832
SKCMGPN3P1 →+0.055+4.328<.001.00732
UCECRNU4-61P →+0.307+1.907<.001.00332
UCECLINC02557 →+0.312+1.486<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,559 associations by consensus.

RN7SL122P by RPL13A expression — CESC

Box plot of RN7SL122P in RPL13A-low vs RPL13A-high samples in CESC.

Explore this box plot interactively →

Exploration