RPL13A

Across TCGA cell cohorts, RPL13A mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPL13A-associated genes across cancer lineages are PPP1R2C, CST8, and SYCN. Each is linked with RPL13A in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL13A-to-partner and partner-to-RPL13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPP1R2C grouped by RPL13A-low versus RPL13A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL13A→partner) and Y-score (partner→RPL13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PPP1R2C →	+0.230	+4.539	<.001	.007	3	1
BLOOD_Leukemia	CST8 →	+0.046	+4.969	<.001	.003	3	1
BLOOD_Leukemia	SYCN →	+0.037	+4.539	<.001	.007	3	1
BLOOD_Leukemia	TMEM95 →	+0.020	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	SLC36A2 →	+0.015	+4.551	<.001	.004	3	1
LARGE_INTESTINE	C6orf118 →	+0.186	+3.793	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

PPP1R2C by RPL13A expression — BLOOD_Leukemia

Explore this box plot interactively →