RPL13

Across TCGA cell cohorts, RPL13 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,754 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RPL13-associated GO terms across cancer lineages are tRNA wobble position uridine thiolation, tRNA thio-modification, and Cytoplasm protein quality control by the ubiquitin-proteasome system. Each is linked with RPL13 in more than 12 cancer types. Because this analysis shows association rather than direction, both RPL13-to-partner and partner-to-RPL13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA wobble position uridine thiolation grouped by RPL13-low versus RPL13-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL13→partner) and Y-score (partner→RPL13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	tRNA wobble position uridine thiolation →	+0.101	+1.132	<.001	<.001	3	13
LUNG_SCLC	tRNA thio-modification →	+0.137	+1.191	<.001	<.001	3	11
BONE	Cytoplasm protein quality control by the ubiquitin-proteasome system →	+0.158	+1.080	<.001	<.001	3	11
LUNG_SCLC	Protein urmylation →	+0.086	+1.092	.001	<.001	3	10
BONE	Cytoplasm protein quality control →	+0.149	+1.080	<.001	<.001	3	10
LUNG_SCLC	Peptidyl-methionine modification →	+0.215	+1.169	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,754 associations by consensus.

tRNA wobble position uridine thiolation by RPL13 expression — LUNG_SCLC

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