RPL12P47

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL12P47 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of RPL12P47’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPL12P47 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL12P47 is over-expressed in tumor, although a few such as BRCA and BLCA show the opposite, repressed pattern.

COAD, BRCA, and BLCA are the cancer types where RPL12P47 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL12P47 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADFemaleII,III,IV+2.118<.0018view →
BRCAAllIV−1.174<.0018view →
BLCAMaleAll−0.459.0234view →
KIRCFemaleIV−0.441.0013view →
KIRPMaleAll−0.314.0033view →
LIHCAllAll+0.207<.0013view →
STADAllIV+1.363.0102view →
KICHFemaleII,III,IV−0.458.0202view →
THCAAllAll−0.289.0112view →
KIRCMaleAll+0.145.0411view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 9 lineages.

Exploration