RPL12P40

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL12P40 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RPL12P40 data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher RPL12P40 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL12P40 expression acts as an unfavorable survival marker, although some lineages such as LUAD and COAD show a favorable association.

ESCA, HNSC, and TGCT are the cancer types where RPL12P40 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ESCAOSTertileIV0.0950.512.00836view →
HNSCDFSTertileAll0.2720.560.01033view →
TGCTDFSTertileAll0.4310.845.00718view →
UCSOSTertileAll0.1830.593.01118view →
ACCDFSTertileII,III,IV0.2420.724.03418view →
STADOSTertileIII,IV0.4980.658.02415view →
SARCOSTertileAll0.6290.842.03912view →
LUADDFSTertileAll0.7910.332.0309view →
COADDFSTertileAll0.8790.498.0443view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

RPL12P40–ESCA (OS)

Kaplan–Meier survival curve for RPL12P40 RNA-high vs -low samples in ESCA.

Open the ESCA breakdown →

Exploration