RPL12P30

Across TCGA pan-cancer cohorts, RPL12P30 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RPL12P30’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL12P30 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL12P30 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, THCA, and KIRP are the cancer types where RPL12P30 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL12P30 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−1.062	<.001	12	view →
THCA	Male	III,IV	−1.868	<.001	11	view →
KIRP	Female	All	−1.210	<.001	11	view →
BRCA	All	III,IV	−0.503	<.001	6	view →
LIHC	All	All	+0.068	.002	3	view →
PRAD	All	All	−0.292	.006	2	view →
HNSC	All	IV	−0.202	.035	2	view →
LUSC	All	All	+0.148	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RPL12P30–KIRC

Open the KIRC breakdown →