RPL12P27

Across TCGA pan-cancer cohorts, RPL12P27 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RPL12P27 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RPL12P27 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RPL12P27 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UVM show a favorable association.

HNSC, UVM, and READ are the cancer types where RPL12P27 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	III,IV	0.702	0.551	<.001	94	view →
UVM	OS	Tertile	All	0.920	0.456	<.001	86	view →
READ	DFS	Tertile	II,III,IV	0.431	0.773	.004	28	view →
KICH	DFS	Median	III,IV	0.336	0.900	.012	25	view →
LGG	OS	Quartile	All	0.918	0.817	.004	25	view →
SARC	DFS	Median	All	0.693	0.530	.001	22	view →
LAML	DFS	Quartile	All	0.242	0.509	.015	18	view →
LUAD	DFS	Median	All	0.827	0.705	.005	17	view →
CESC	DFS	Quartile	III,IV	0.931	0.534	.014	16	view →
OV	OS	Median	II,III,IV	0.287	0.362	.025	12	view →
UCS	OS	Tertile	IV	0.844	0.311	.024	12	view →
UCEC	OS	Quartile	IV	0.336	0.716	.017	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RPL12P27–HNSC (OS)

Open the HNSC breakdown →