RPL12P11

Across TCGA pan-cancer cohorts, RPL12P11 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of RPL12P11’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RPL12P11 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL12P11 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

BRCA, COAD, and PRAD are the cancer types where RPL12P11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL12P11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	IV	+0.470	.015	4	view →
COAD	All	II,III,IV	+0.145	.006	4	view →
PRAD	All	All	+0.218	.007	2	view →
READ	All	III,IV	+0.175	<.001	2	view →
LUSC	Male	All	+0.109	.009	2	view →
KIRC	Male	All	+0.051	.009	2	view →
THCA	Female	III,IV	+0.285	.032	1	view →
LUAD	All	All	+0.247	.030	1	view →
THCA	Male	All	−0.213	.011	1	view →
KICH	Male	III,IV	+0.210	.049	1	view →
STAD	Male	All	+0.131	.041	1	view →
KIRP	All	II,III,IV	+0.071	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 11 lineages.

RPL12P11–BRCA

Open the BRCA breakdown →