RPL11P5

Across TCGA pan-cancer cohorts, RPL11P5 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPL11P5’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPL11P5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL11P5 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

COAD, KIRC, and THCA are the cancer types where RPL11P5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL11P5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.205	.033	4	view →
KIRC	Male	II,III,IV	−0.068	.006	2	view →
THCA	Female	All	−0.062	.009	2	view →
KIRC	Female	All	+0.067	.018	1	view →
KICH	All	All	−0.032	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 4 lineages.

RPL11P5–COAD

Open the COAD breakdown →