Across TCGA pan-cancer cohorts, RPL10AP5 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPL10AP5’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where RPL10AP5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL10AP5 is over-expressed in tumor, although a few such as KIRP and BLCA show the opposite, repressed pattern.
LUAD, KIRP, and BLCA are the cancer types where RPL10AP5 tumor–normal differential expression is most reproducible.