RPL10AP1

Across TCGA pan-cancer cohorts, RPL10AP1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RPL10AP1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPL10AP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL10AP1 is over-expressed in tumor, although a few such as KICH and STAD show the opposite, repressed pattern.

COAD, HNSC, and LIHC are the cancer types where RPL10AP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL10AP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+0.692	<.001	7	view →
HNSC	All	All	+0.099	.002	5	view →
LIHC	Male	All	+0.069	.001	4	view →
KICH	Female	All	−0.149	.022	3	view →
STAD	Male	III,IV	−0.596	.006	2	view →
BRCA	All	IV	−0.520	.005	2	view →
CHOL	Male	All	+0.150	.038	2	view →
ESCA	All	All	−0.439	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RPL10AP1–COAD

Open the COAD breakdown →