Across TCGA patient cohorts, RPL10A mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL10A-associated genes across cancer lineages are EGFR_pY1068, ERK2, and Ku80. Each is linked with RPL10A in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL10A-to-partner and partner-to-RPL10A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL10A→partner) and Y-score (partner→RPL10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.469	-3.169	<.001	.020	3	1
UCEC	ERK2 →	+0.245	+3.169	.020	.020	3	1
UCEC	Ku80 →	+0.284	+3.183	.028	.010	3	1
UCEC	Annexin-1 →	+0.985	+2.999	<.001	.035	3	1
UCEC	Smad3 →	+0.204	+3.000	.013	.036	3	1
UCEC	Bax →	+0.280	+2.817	.033	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

RPL10A survival (RNA) · tumor vs normal (RNA) · all RPL10A data types