RPL10

Across TCGA pan-cancer cohorts, RPL10 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RPL10 data layer compared with 21 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RPL10 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RPL10 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

CCRCC, LUAD, and HNSC are the cancer types where RPL10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	All	0.714	1.000	.001	34	view →
LUAD	DFS	Tertile	III,IV	0.875	0.308	.002	19	view →
HNSC	DFS	Quartile	All	0.335	1.000	.036	8	view →
GBM	DFS	Quartile	All	0.243	0.503	.032	6	view →
LSCC	OS	Median	All	0.806	1.000	.045	1	view →
PDAC	OS	Median	All	0.721	0.913	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RPL10–CCRCC (OS)

Open the CCRCC breakdown →