Across TCGA pan-cancer cohorts, RPF2 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated RPF2 data layer compared with 22 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RPF2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RPF2 expression acts as an unfavorable survival marker.

COAD are the cancer types where RPF2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.117	0.809	<.001	24	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: RPF2 tumor-vs-normal RNA expression · all RPF2 data types