Across TCGA patient cohorts, RPF2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,216 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RPF2-associated genes across cancer lineages are RRS1, UBE2C, and SLC52A2. Each is linked with RPF2 in more than 6 cancer types. Because this analysis shows association rather than direction, both RPF2-to-partner and partner-to-RPF2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPF2→partner) and Y-score (partner→RPF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RRS1 →	+0.723	+0.262	.004	.006	3	7
BRCA	UBE2C →	+1.439	+0.654	<.001	<.001	3	6
BRCA	SLC52A2 →	+0.784	+0.581	<.001	<.001	3	6
BRCA	KANK2 →	-0.825	-0.450	<.001	<.001	3	6
CCRCC	RAD54B →	+0.686	+0.319	<.001	<.001	3	6
LSCC	SNHG3 →	+0.768	+0.386	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,216 associations by consensus.

Exploration

RPF2 survival (RNA) · tumor vs normal (RNA) · all RPF2 data types