Q-omics provides the consensus-scored RPEP1 profile across patient tissues and cancer cell-line models. RPEP1 expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, RPEP1 is differentially expressed in 2, with the highest sampling consensus in STAD. Additionally, RPEP1 RNA expression shows 10,096 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight UCS, STAD, and GBM as cancer lineages where RPEP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPEP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPEP1 survival associations across molecular data types. RPEP1 RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPEP1 RNA expression–survival associations across cancer types. High RPEP1 expression shows unfavorable associations in UCS, SKCM, LIHC, OV, PRAD and ACC. The UCS Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .048). Together, the overview and detailed table identify UCS as the clearest survival context for RPEP1 RNA expression.
This table summarizes RPEP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in STAD for RNA.
This table ranks reproducible tumor–normal expression differences for RPEP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPEP1 shows higher tumor expression in STAD and BRCA. The STAD box plot shows higher RPEP1 RNA expression in tumor versus normal tissue (log2 FC = +0.046, t-test p = .015).
This table shows molecular features associated with RPEP1 in patient tissues and cancer cell lines. In patient samples, RPEP1 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
