Across TCGA cell cohorts, RPE RNA expression is significantly associated with the go_rna of many other GO terms, with 3,062 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RPE-associated GO terms across cancer lineages are Centromeric sister chromatid cohesion, Regulation of cell cycle G2/M phase transition, and Positive regulation of cell cycle process. Each is linked with RPE in more than 14 cancer types. Because this analysis shows association rather than direction, both RPE-to-partner and partner-to-RPE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPE→partner) and Y-score (partner→RPE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Centromeric sister chromatid cohesion →	+0.149	+0.652	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of cell cycle G2/M phase transition →	+0.097	+1.529	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle process →	+0.104	+1.215	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of G2/M transition of mitotic cell cycle →	+0.108	+1.454	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle G2/M phase transition →	+0.086	+0.911	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Mitotic G2/M transition checkpoint →	+0.109	+1.262	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,062 associations by consensus.

Exploration

RPE survival (RNA) · tumor vs normal (RNA) · all RPE data types