RPAP2

Across TCGA cell cohorts, RPAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,507 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RPAP2-associated GO terms across cancer lineages are Positive regulation of centriole replication, Zinc ion import into Golgi lumen, and Protein localization to condensed chromosome. Each is linked with RPAP2 in more than 14 cancer types. Because this analysis shows association rather than direction, both RPAP2-to-partner and partner-to-RPAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of centriole replication grouped by RPAP2-low versus RPAP2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPAP2→partner) and Y-score (partner→RPAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of centriole replication →	+0.131	+0.673	<.001	.004	3	15
SKIN	Zinc ion import into Golgi lumen →	+0.094	+0.549	<.001	.006	3	12
STOMACH	Protein localization to condensed chromosome →	+0.130	+0.650	<.001	.002	3	12
STOMACH	Protein localization to kinetochore →	+0.136	+0.727	.002	.005	3	11
UPPER_AERODIGESTIVE_TRACT	Telomeric 3' overhang formation →	+0.169	+0.639	<.001	.002	3	10
LARGE_INTESTINE	Negative regulation of cell cycle G2/M phase transition →	+0.057	+0.679	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,507 associations by consensus.

Positive regulation of centriole replication by RPAP2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →