RPAP1

Across TCGA patient cohorts, RPAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,581 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPAP1-associated genes across cancer lineages are SPATA5L1, MAPKBP1, and CDAN1. Each is linked with RPAP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both RPAP1-to-partner and partner-to-RPAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPAP1 versus SPATA5L1 in OV, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPAP1→partner) and Y-score (partner→RPAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SPATA5L1 →	+0.521	+0.218	.001	.004	3	5
LSCC	MAPKBP1 →	+0.645	+0.151	<.001	.004	3	4
UCEC	CDAN1 →	+0.418	+0.125	<.001	<.001	3	4
UCEC	CYC1 →	+0.774	+0.120	.008	.009	3	4
BRCA	NGRN →	+0.662	+0.150	.001	.003	3	4
UCEC	MFAP1 →	+0.713	+0.156	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,581 associations by consensus.

RPAP1 vs SPATA5L1 — OV

Explore this scatter interactively →