RPAP1

Across TCGA patient cohorts, RPAP1 protein abundance is significantly associated with the protein abundance of many other proteins, with 14,388 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPAP1-associated proteins across cancer lineages are GPN1, GCN1, and UNC45A. Each is linked with RPAP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both RPAP1-to-partner and partner-to-RPAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPAP1 versus GPN1 in PDAC, with a Pearson correlation of 0.36.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPAP1→partner) and Y-score (partner→RPAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	GPN1 →	+0.259	+0.279	.009	.002	1	7
LSCC	GCN1 →	+0.334	+0.231	<.001	<.001	3	5
LSCC	UNC45A →	+0.212	+0.124	.001	<.001	2	5
LSCC	NOC2L →	+0.594	+0.239	<.001	<.001	3	4
GBM	POLR2B →	+0.206	+0.148	<.001	<.001	3	4
BRCA	GPN1_S338 →	+0.671	+0.211	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,388 associations by consensus.

RPAP1 vs GPN1 — PDAC

Explore this scatter interactively →