RPAIN

Across TCGA cell cohorts, RPAIN RNA expression is significantly associated with the go_rna of many other GO terms, with 5,102 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPAIN-associated GO terms across cancer lineages are Adult walking behavior, rRNA methylation, and Skin development. Each is linked with RPAIN in more than 12 cancer types. Because this analysis shows association rather than direction, both RPAIN-to-partner and partner-to-RPAIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adult walking behavior grouped by RPAIN-low versus RPAIN-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPAIN→partner) and Y-score (partner→RPAIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Adult walking behavior →	+0.625	+0.709	.008	.008	3	13
UPPER_AERODIGESTIVE_TRACT	rRNA methylation →	+0.080	+0.773	<.001	.001	3	12
URINARY_TRACT	Skin development →	-0.152	-0.896	.002	.001	3	12
BONE	Regulation of body fluid levels →	-0.086	-1.019	.001	<.001	2	12
OVARY	'de novo' IMP biosynthetic process →	+0.129	+0.877	<.001	<.001	3	11
LUNG_SCLC	Positive regulation of double-strand break repair via nonhomologous end joining →	+0.086	+0.933	.002	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,102 associations by consensus.

Adult walking behavior by RPAIN expression — BONE

Explore this box plot interactively →