RPA3P1

Across TCGA pan-cancer cohorts, RPA3P1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RPA3P1 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RPA3P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPA3P1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and READ show a favorable association.

LUSC, BLCA, and OV are the cancer types where RPA3P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	II,III,IV	0.417	0.817	.001	57	view →
BLCA	DFS	Tertile	IV	0.245	0.486	.008	54	view →
OV	OS	Quartile	II,III,IV	0.772	0.879	<.001	54	view →
UCS	OS	Tertile	II,III,IV	0.231	0.634	.011	36	view →
SARC	DFS	Tertile	All	0.088	0.595	<.001	27	view →
ESCA	DFS	Median	All	0.283	0.427	.012	21	view →
SKCM	OS	Tertile	IV	0.263	0.660	.025	18	view →
UCEC	DFS	Tertile	IV	0.935	0.584	.018	12	view →
READ	DFS	Tertile	All	0.875	0.653	.029	12	view →
LUAD	OS	Tertile	III,IV	0.222	0.530	.043	9	view →
PAAD	DFS	Tertile	II,III,IV	0.233	0.443	.028	9	view →
GBM	OS	Tertile	All	0.199	0.291	.015	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RPA3P1–LUSC (OS)

Open the LUSC breakdown →