RPA3

Across TCGA patient cohorts, RPA3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,178 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPA3-associated proteins across cancer lineages are PCNA, RRM2, and RRM2_S20. Each is linked with RPA3 in more than 6 cancer types. Because this analysis shows association rather than direction, both RPA3-to-partner and partner-to-RPA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPA3 versus PCNA in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPA3→partner) and Y-score (partner→RPA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PCNA →	+0.579	+0.579	<.001	<.001	3	7
GBM	RRM2 →	+0.846	+0.453	<.001	<.001	3	7
LSCC	RRM2_S20 →	+0.817	+0.557	<.001	<.001	3	7
LSCC	HAT1 →	+0.558	+0.582	<.001	<.001	3	7
GBM	LIG1 →	+0.631	+0.461	<.001	<.001	3	7
GBM	MCM2 →	+0.620	+0.417	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,178 associations by consensus.

RPA3 vs PCNA — LSCC

Explore this scatter interactively →